Title : Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation.

Pub. Date : 2010 Apr 13

PMID : 20351270






1 Functional Relationships(s)
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1 The presence of EGF was coupled to preferential E6 expression, whereas depletion of EGF, or treatment with EGF receptor (EGFR) neutralizing antibodies or the EGFR inhibitor tyrphostin AG1478, resulted in E6 exon exclusion in favor of E6*. Tyrphostins epidermal growth factor receptor Homo sapiens