Title : Investigation of structure-activity relationships in organophosphates-cholinesterase interaction using docking analysis.

Pub. Date : 2010 Sep 6

PMID : 20347727






1 Functional Relationships(s)
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1 In addition to well-known residues 288 and 290 (Torpedo AChE sequence numbering), we showed an essential influence of residue 400 - a short alkyl residue in mammalian ChEs and phenylalanine in insect ChEs. Phenylalanine acetylcholinesterase (Cartwright blood group) Homo sapiens