Pub. Date : 2010 Jul
PMID : 20339915
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calcium induces expression of cytoplasmic gelsolin in SH-SY5Y and HEK-293 cells. | Calcium | gelsolin | Homo sapiens |
| 2 | We report here that calcium ionophore A23187 induces the expression of cytoplasmic gelsolin (c-gelsolin), and that protein kinase C (PKC) is involved in the up-regulation of c-gelsolin. | Calcium | gelsolin | Homo sapiens |
| 3 | We report here that calcium ionophore A23187 induces the expression of cytoplasmic gelsolin (c-gelsolin), and that protein kinase C (PKC) is involved in the up-regulation of c-gelsolin. | Calcium | gelsolin | Homo sapiens |
| 4 | We report here that calcium ionophore A23187 induces the expression of cytoplasmic gelsolin (c-gelsolin), and that protein kinase C (PKC) is involved in the up-regulation of c-gelsolin. | Calcium | gelsolin | Homo sapiens |
| 5 | In the presence of calcium, both SH-SY5Y and HEK-293 cells upon treatment with A23187 showed an increase in c-gelsolin expression in a concentration-dependent manner. | Calcium | gelsolin | Homo sapiens |
| 6 | Calcium-mediated up-regulation of c-gelsolin was inhibited by cycloheximide (a general inhibitor of protein synthesis). | Calcium | gelsolin | Homo sapiens |
| 7 | These results suggest that calcium mediates up-regulation of c-gelsolin in a PKC-dependent manner. | Calcium | gelsolin | Homo sapiens |