Pub. Date : 2010 Feb
PMID : 20332437
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sulindac sulfone induces a decrease of beta-catenin in HNSCC. | sulindac sulfone | catenin beta 1 | Homo sapiens |
| 2 | In the present study, we surveyed the concentration of beta-catenin in an HNSCC line after incubation with different concentrations of sulindac sulfone. | sulindac sulfone | catenin beta 1 | Homo sapiens |
| 3 | RESULTS: At 100 microMol of sulindac sulfone, a decrease in beta-catenin concentration of 5% was observed; increasing concentrations of sulindac sulfone resulted in >70% reduction in secreted beta-catenin. | sulindac sulfone | catenin beta 1 | Homo sapiens |
| 4 | RESULTS: At 100 microMol of sulindac sulfone, a decrease in beta-catenin concentration of 5% was observed; increasing concentrations of sulindac sulfone resulted in >70% reduction in secreted beta-catenin. | sulindac sulfone | catenin beta 1 | Homo sapiens |
| 5 | CONCLUSION: In this study, sulindac sulfone reduced levels of secreted beta-catenin in the HNSCC cell line UM-SCC 11A after 48 hours of incubation. | sulindac sulfone | catenin beta 1 | Homo sapiens |