Title : Newborn serum retinoic acid level is associated with variants of genes in the retinol metabolism pathway.

Pub. Date : 2010 Jun

PMID : 20308937






3 Functional Relationships(s)
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1 However, we found that the (A) allele of the rs12591551 single nucleotide polymorphism (SNP) in the ALDH1A2 gene (ALDH1A2rs12591551(A)), occurring in 19% of newborns, was associated with 2.5-fold higher serum RA levels. Tretinoin aldehyde dehydrogenase 1 family member A2 Homo sapiens
2 However, we found that the (A) allele of the rs12591551 single nucleotide polymorphism (SNP) in the ALDH1A2 gene (ALDH1A2rs12591551(A)), occurring in 19% of newborns, was associated with 2.5-fold higher serum RA levels. Tretinoin aldehyde dehydrogenase 1 family member A2 Homo sapiens
3 ALDH1A2 encodes retinaldehyde dehydrogenase (RALDH) 2, which synthesizes RA in fetal tissues. Tretinoin aldehyde dehydrogenase 1 family member A2 Homo sapiens