Pub. Date : 2010 Mar 22
PMID : 20308640
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The opioid effect is mainly mediated by (R)-methadone, whereas (S)-methadone blocks the human ether-a-go-go-related gene (hERG) voltage-gated potassium channel more potently, which can cause drug-induced long QT syndrome, leading to potentially lethal ventricular tachyarrhythmias. | Methadone | ETS transcription factor ERG | Homo sapiens |