Title : IL-1 expression in human monocytes is transcriptionally and posttranscriptionally regulated by IL-4.

Pub. Date : 1991 May 15

PMID : 2026872






2 Functional Relationships(s)
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Protein Name
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1 The initial 2 to 3 h lag period may be necessary for production of a protein(s) that mediates this inhibitory effect because treatment with the protein synthesis inhibitor, cycloheximide, blocked the marked reduction of IL-1 message levels induced by IL-4. Cycloheximide interleukin 4 Homo sapiens
2 In addition, the kinetics of inhibition and the fact that cycloheximide blocks this process suggest that IL-4 induces or enhances synthesis of a protein(s) that mediates these effects. Cycloheximide interleukin 4 Homo sapiens