Title : Recombinant human VEGF165b inhibits experimental choroidal neovascularization.

Pub. Date : 2010 Aug

PMID : 20237252






1 Functional Relationships(s)
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1 After laser injury, mice were injected either intraocularly or subcutaneously with recombinant human VEGF-A(165)b. Intraocular injection of rhVEGF-A(165)b gave a pronounced dose-dependent inhibition of fluorescein leakage, with an IC(50) of 16 pg/eye, neovascularization (IC(50), 0.8 pg/eye), and lesion as assessed by histologic staining (IC(50), 8 pg/eye). Fluorescein vascular endothelial growth factor A Homo sapiens