Title : CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cells.

Pub. Date : 2010 Jun

PMID : 20233841






3 Functional Relationships(s)
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1 By using the CYP3A4-specific substrates luciferin 6" benzyl ether, testosterone, and midazolam, we could confirm that the increased CYP3A4 gene expression also was accompanied by a similar increase in catalytic activity, inhibitable by the CYP3A4-selective inhibitor ketoconazole. luciferin 6" benzyl ether cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 By using the CYP3A4-specific substrates luciferin 6" benzyl ether, testosterone, and midazolam, we could confirm that the increased CYP3A4 gene expression also was accompanied by a similar increase in catalytic activity, inhibitable by the CYP3A4-selective inhibitor ketoconazole. luciferin 6" benzyl ether cytochrome P450 family 3 subfamily A member 4 Homo sapiens
3 By using the CYP3A4-specific substrates luciferin 6" benzyl ether, testosterone, and midazolam, we could confirm that the increased CYP3A4 gene expression also was accompanied by a similar increase in catalytic activity, inhibitable by the CYP3A4-selective inhibitor ketoconazole. luciferin 6" benzyl ether cytochrome P450 family 3 subfamily A member 4 Homo sapiens