Pub. Date : 2010 Sep
PMID : 20230877
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Subchronic administration of rosmarinic acid, a natural prolyl oligopeptidase inhibitor, enhances cognitive performances. | rosmarinic acid | prolyl endopeptidase | Homo sapiens |
2 | In this study, we observed that rosmarinic acid (RA) inhibits POP activity with an IC(50) of 63.7 microM. | rosmarinic acid | prolyl endopeptidase | Homo sapiens |
3 | In this study, we observed that rosmarinic acid (RA) inhibits POP activity with an IC(50) of 63.7 microM. | rosmarinic acid | prolyl endopeptidase | Homo sapiens |
4 | The results demonstrated that RA is non-competitive POP inhibitor and that acute and subchronic RA treatments showed an inverted U-shaped dose-response curve in the platform crossings. | rosmarinic acid | prolyl endopeptidase | Homo sapiens |
5 | The results demonstrated that RA is non-competitive POP inhibitor and that acute and subchronic RA treatments showed an inverted U-shaped dose-response curve in the platform crossings. | rosmarinic acid | prolyl endopeptidase | Homo sapiens |
6 | These results suggest that RA has a cognitive-enhancing effect which may be mediated by inhibition of POP. | rosmarinic acid | prolyl endopeptidase | Homo sapiens |