Title : The role of cyclooxygenase (COX)-2 derived prostanoids on vasoconstrictor responses to phenylephrine is increased by exposure to low mercury concentration.

Pub. Date : 2010 Feb

PMID : 20228412






3 Functional Relationships(s)
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1 The aim of this work was to investigate if mercury exposure alters contractile prostanoids production from cyclooxygenase-2 (COX-2) and its contribution to phenylephrine responses. Prostaglandins prostaglandin-endoperoxide synthase 2 Rattus norvegicus
2 The aim of this work was to investigate if mercury exposure alters contractile prostanoids production from cyclooxygenase-2 (COX-2) and its contribution to phenylephrine responses. Prostaglandins prostaglandin-endoperoxide synthase 2 Rattus norvegicus
3 These results suggest that treatment with low doses of mercury increases the release of COX-2-derived vasoconstrictor prostanoids and its participation in phenylephrine responses. Prostaglandins prostaglandin-endoperoxide synthase 2 Rattus norvegicus