Title : Cyclophosphamide dose intensification may circumvent anthracycline resistance of p53 mutant breast cancers.

Pub. Date : 2010

PMID : 20228131






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclophosphamide dose intensification may circumvent anthracycline resistance of p53 mutant breast cancers. Cyclophosphamide tumor protein p53 Homo sapiens
2 A sharp statistical interaction was detected between p53 status and cyclophosphamide dose intensity. Cyclophosphamide tumor protein p53 Homo sapiens
3 Thus, our data strongly suggest that cyclophosphamide dose intensification in ER(-) p53-mutated breast cancer patients could significantly improve their response. Cyclophosphamide tumor protein p53 Homo sapiens