Title : Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E.

Pub. Date : 2010 Mar 16

PMID : 20227039






1 Functional Relationships(s)
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Protein Name
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1 While phosphorylation of rpS6 is dispensable for cancer formation, 4EBP-eIF4E exerts significant control over cap-dependent translation, cell growth, cancer initiation, and progression. cap eukaryotic translation initiation factor 4E Homo sapiens