Title : Synergistic antitumor activity of interleukin-2 and cimetidine against syngeneic murine tumor.

Pub. Date : 1991

PMID : 2021961






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The treatment of IL-2 plus cimetidine increased NK and LAK cell activities significantly and synergistically at the end of the treatment (i.e. on day 18) as well as 1 week after the treatment (i.e. on day 25), in comparison with those of the control groups (PBS, cimetidine alone, IL-2 alone). pbs interleukin 2 Mus musculus
2 A significant increase in asialo GM1-positive cells and IL-2-receptor-positive cells was detected in the group treated with IL-2 plus cimetidine in comparison with the PBS and IL-2 control groups. pbs interleukin 2 Mus musculus
3 A significant increase in asialo GM1-positive cells and IL-2-receptor-positive cells was detected in the group treated with IL-2 plus cimetidine in comparison with the PBS and IL-2 control groups. pbs interleukin 2 Mus musculus