Title : Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo.

Pub. Date : 2010 Jun-Jul

PMID : 20214874






1 Functional Relationships(s)
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1 Ruthenium red (RuR), AzRu, DIDS and hexokinase-I (HK-I), all known to interact with VDAC, inhibited the release of cytochrome c, Smac/Diablo and AIF, while RuR-mediated inhibition was not observed in cells expressing RuR-insensitive E72Q-VDAC1. Ruthenium Red cytochrome c, somatic Homo sapiens