Title : Chronic exposure to a high-fat diet affects stress axis function differentially in diet-induced obese and diet-resistant rats.

Pub. Date : 2010 Jul

PMID : 20212497






1 Functional Relationships(s)
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1 We hypothesized that consumption of an HF diet activates HPA axis by increasing norepinephrine (NE) in the paraventricular nucleus (PVN) of the hypothalamus, leading to elevation in corticotrophin-releasing hormone (CRH) concentration in the median eminence (ME) resulting in elevated serum corticosterone (CORT). Norepinephrine corticotropin releasing hormone Rattus norvegicus