Pub. Date : 2010 Mar 23
PMID : 20212108
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | JNK activity was detected not only in the cytoplasm, but also in the nucleus, mitochondria, and plasma membrane with similar kinetics after induction of ribotoxic stress by anisomycin, suggesting relatively rapid signal propagation to the nuclear, mitochondrial, and plasma membrane compartments. | Anisomycin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Furthermore, quantitative single-cell analysis revealed that anisomycin-induced JNK activity exhibited ultrasensitivity, sustainability, and bimodality, features that are consistent with behaviors of bistable systems. | Anisomycin | mitogen-activated protein kinase 8 | Homo sapiens |