Title : The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.

Pub. Date : 2010 Mar 4

PMID : 20209098






1 Functional Relationships(s)
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1 In aortic tissue, vascular relaxant effects of GW0742 were not associated with increases in cGMP, cAMP or hyperpolarisation, but were attributed to inhibition of RhoA activity. GW0742 ras homolog family member A Rattus norvegicus