Title : Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling.

Pub. Date : 2010 Apr

PMID : 20197310






2 Functional Relationships(s)
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1 Both 17beta-estradiol (E2) and G1, a compound reported to be a selective GPR30 agonist, increased the phosphorylation levels of the MAPK/ERK1/2 in SK-BR-3 cells, which could be blocked by an anti-ER-alpha36-specific antibody against its ligand-binding domain. Estradiol mitogen-activated protein kinase 3 Homo sapiens
2 Both 17beta-estradiol (E2) and G1, a compound reported to be a selective GPR30 agonist, increased the phosphorylation levels of the MAPK/ERK1/2 in SK-BR-3 cells, which could be blocked by an anti-ER-alpha36-specific antibody against its ligand-binding domain. Estradiol mitogen-activated protein kinase 3 Homo sapiens