Title : Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase.

Pub. Date : 2010 Aug

PMID : 20192902






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Oxime K027 is a low-toxic bisquaternary compound originally developed as a reactivator of acetylcholinesterase (AChE) inhibited by nerve agents. oxime k027 acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Oxime K027 is a low-toxic bisquaternary compound originally developed as a reactivator of acetylcholinesterase (AChE) inhibited by nerve agents. oxime k027 acetylcholinesterase (Cartwright blood group) Homo sapiens
3 The results show that oxime K027 reactivated AChE inhibited by almost all tested inhibitors to more than 10%, which is believed to be enough for saving the lives of intoxicated organisms. oxime k027 acetylcholinesterase (Cartwright blood group) Homo sapiens
4 In the case of cyclosarin- and soman-inhibited AChE, oxime K027 did not reach sufficient reactivation potency. oxime k027 acetylcholinesterase (Cartwright blood group) Homo sapiens