Title : Nerve growth factor as a paradigm of neurotrophins related to Alzheimer's disease.

Pub. Date : 2010 Apr

PMID : 20186703






1 Functional Relationships(s)
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1 At the same time tau protein undergoes anomalous, GSKbeta-mediated, phosphorylation at specific pathogenetic sites (Ser262 and Thr 231), caspase(s) and calpain- I- mediated truncation, detachment from microtubules with consequent cytoskeleton collapse and axonal transport impairment. Threonine microtubule associated protein tau Homo sapiens