Title : A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition.

Pub. Date : 2010 Apr 23

PMID : 20185821






1 Functional Relationships(s)
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1 Activation of FXR by the synthetic agonist GW4064 decreases hepatic miR-34a levels in normal mice, and consistently, hepatic miR-34a levels are elevated in FXR-null mice. GW 4064 microRNA 34a Mus musculus