Title : Mass spectroscopy and molecular modeling predict endothelial nitric oxide synthase dimer collapse by hydrogen peroxide through zinc tetrathiolate metal-binding site disruption.

Pub. Date : 2010 Mar

PMID : 20184449






4 Functional Relationships(s)
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Protein Name
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1 Mass spectroscopy and molecular modeling predict endothelial nitric oxide synthase dimer collapse by hydrogen peroxide through zinc tetrathiolate metal-binding site disruption. Hydrogen Peroxide nitric oxide synthase 3 Homo sapiens
2 Endothelial nitric oxide synthase (eNOS) is inhibited by hydrogen peroxide (H(2)O(2)), but the mechanism has not been determined. Hydrogen Peroxide nitric oxide synthase 3 Homo sapiens
3 Endothelial nitric oxide synthase (eNOS) is inhibited by hydrogen peroxide (H(2)O(2)), but the mechanism has not been determined. Hydrogen Peroxide nitric oxide synthase 3 Homo sapiens
4 Thus, the purpose of this study was to delineate the mechanism by which H(2)O(2) inhibits eNOS activity. Hydrogen Peroxide nitric oxide synthase 3 Homo sapiens