Pub. Date : 2010 Mar 15
PMID : 20179103
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | However, only active Mek2 could bind Pin1, acting as a scaffold to bridge Pin1 and BPGAP1 in a manner that involves the release of an autoinhibited proline-rich motif, 186-PPLP-189, proximal to the RhoGAP domain. | Proline | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | Homo sapiens |
2 | This allows the non-canonical 186-PPLP-189 and 256-DDYGD-260 motifs of the proline-rich region and RhoGAP domain of BPGAP1 to become accessible to concerted binding by the WW and PPI domains of Pin1, respectively. | Proline | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | Homo sapiens |