Title : Protection of p53 wild type cells from taxol by nutlin-3 in the combined lung cancer treatment.

Pub. Date : 2010 Feb 23

PMID : 20178585






1 Functional Relationships(s)
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1 The aim of this study was to selectively kill p53 deficient cells (FaDu and H1299) by taxol and to protect p53 wild type cells (A549) by the prior administration of nutlin-3 in comparison to certain known anticancer drugs (5-fluorouracil, camptothecin, roscovitine). nutlin 3 tumor protein p53 Homo sapiens