Pub. Date : 1991 Apr
PMID : 2017664
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Addition of monocytes to highly purified T cells stimulated with ionomycin resulted in partial reconstitution of IL-2 production, IL-2R expression and proliferation. | Ionomycin | interleukin 2 | Homo sapiens |
| 2 | Similarly, the addition of exogenous IL-2 to ionomycin-stimulated T cells only partially reconstituted the response compared with PBMC. | Ionomycin | interleukin 2 | Homo sapiens |
| 3 | With ionomycin, monocytes play a role, in part, in inducing IL-2 production, IL-2R expression and proliferation. | Ionomycin | interleukin 2 | Homo sapiens |
| 4 | However, IL-2 is not a sufficient signal to induce T-cell proliferative response to ionomycin, suggesting that an IL-2-independent mechanism may exist in ionomycin-induced T-cell proliferation. | Ionomycin | interleukin 2 | Homo sapiens |