Pub. Date : 2009 Dec
PMID : 20175801
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fluconazole, an antifungal agent and an inhibitor of CYP3A4 is an established part of the therapy in HIV patients, who in turn are prone to malaria in the tropics. | Fluconazole | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | CONCLUSION: The decreased plasma concentrations of the metabolite are presumably caused by metabolic inhibition of CYP3A4 by fluconazole. | Fluconazole | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |