Title : Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis.

Pub. Date : 2010 May 15

PMID : 20171273






1 Functional Relationships(s)
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1 By the use of either small interfering RNAs to target SIRT1 or the SIRT1 inhibitor nicotinamide we found that Nox1-dependent inhibition of p53 transcriptional activity was SIRT1-dependent. Niacinamide tumor protein p53 Homo sapiens