Title : Dissociation of growth hormone and prolactin response to levodopa during pyridoxine administration.

Pub. Date : 1977 Jul

PMID : 20170






5 Functional Relationships(s)
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1 Dissociation of growth hormone and prolactin response to levodopa during pyridoxine administration. Levodopa prolactin Homo sapiens
2 500 mg of levodopa was administered orally to 8 normal subjects and induced an increase of growth hormone (GH) and a decrease of prolactin (PRL) secretion. Levodopa prolactin Homo sapiens
3 500 mg of levodopa was administered orally to 8 normal subjects and induced an increase of growth hormone (GH) and a decrease of prolactin (PRL) secretion. Levodopa prolactin Homo sapiens
4 The levodopa-induced GH release was inhibited by an intravenous infusion of pyridoxine; on the contrary, the PRL response to levodopa was enhanced by pyridoxine infusion. Levodopa prolactin Homo sapiens
5 This dissociation of GH and PRL responses to levodopa during pyridoxine infusion appears to be mediated by peripheral acceleration of the conversion of levodopa to dopamine. Levodopa prolactin Homo sapiens