Title : Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I.

Pub. Date : 2010 Mar

PMID : 20170205






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Influence of the CYP3A5 6986A>G SNP on the pharmacokinetics of ciclosporin is also uncertain and likely to be small. Cyclosporine cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 CYP3A4 may play a more dominant role than CYP3A5 in the metabolism of ciclosporin. Cyclosporine cytochrome P450 family 3 subfamily A member 5 Homo sapiens