Title : TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1.

Pub. Date : 2010 Aug

PMID : 20168333






1 Functional Relationships(s)
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1 Nevertheless, simultaneous disruption of the p38 MAPK pathway was required to suppress MCL-1 expression, thereby allowing tBID to activate the proapoptotic BCL-2 family member BAK and stimulate mitochondrial outer membrane permeabilization (MOMP). tBID BCL2 apoptosis regulator Homo sapiens