Title : HMGB1 activates nuclear factor-κB signaling by RAGE and increases the production of TNF-α in human umbilical vein endothelial cells.

Pub. Date : 2010 Dec

PMID : 20163887






1 Functional Relationships(s)
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1 Additionally, the HMGB1-induced activation of HUVECs was significantly inhibited by anti-RAGE monoclonal antibody and Ethyl pyruvate (EP) that had been shown to be an effective anti-inflammatory agent. ethyl pyruvate high mobility group box 1 Homo sapiens