Title : 'Prion-like' propagation of mouse and human tau aggregates in an inducible mouse model of tauopathy.

Pub. Date : 2010

PMID : 20160454






1 Functional Relationships(s)
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1 In addition, both types of human tau derivatives were expressed in a "proaggregant" form (with the frontotemporal dementia with parkinsonism linked to chromosome 17 mutation DeltaK280), or in an "antiaggregant" form (with additional proline mutations to block beta-structure and aggregation). Proline microtubule associated protein tau Homo sapiens