Title : ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.

Pub. Date : 2010 Mar 2

PMID : 20160076






2 Functional Relationships(s)
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1 Importantly, elevated ROS and dysregulation of mTORC1 in ATM-deficient cells is inhibited by rapamycin, which also rescues lymphomagenesis in Atm-deficient mice. Sirolimus ataxia telangiectasia mutated Mus musculus
2 Importantly, elevated ROS and dysregulation of mTORC1 in ATM-deficient cells is inhibited by rapamycin, which also rescues lymphomagenesis in Atm-deficient mice. Sirolimus ataxia telangiectasia mutated Mus musculus