Pub. Date : 2010 Mar 1
PMID : 20160032
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate. | ethyl pyruvate | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 2 | In this report, we offer preclinical evidence that the low-cost, anti-inflammatory agent ethyl pyruvate elicits a potent immune-based antitumor response through inhibition of indoleamine 2,3-dioxygenase (IDO), a key tolerogenic enzyme for many human tumors. | ethyl pyruvate | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 3 | In this report, we offer preclinical evidence that the low-cost, anti-inflammatory agent ethyl pyruvate elicits a potent immune-based antitumor response through inhibition of indoleamine 2,3-dioxygenase (IDO), a key tolerogenic enzyme for many human tumors. | ethyl pyruvate | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 4 | Consistent with its reported ability to interfere with NF-kappaB function, ethyl pyruvate blocks IDO induction both in vitro and in vivo. | ethyl pyruvate | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 5 | Our findings that IDO is effectively blocked by ethyl pyruvate treatment deepen emerging links between IDO and inflammatory processes. | ethyl pyruvate | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 6 | Our findings that IDO is effectively blocked by ethyl pyruvate treatment deepen emerging links between IDO and inflammatory processes. | ethyl pyruvate | indoleamine 2,3-dioxygenase 1 | Homo sapiens |