Title : [Effect of FK506 on cytokine secretion in whole blood].

Pub. Date : 2010 Feb

PMID : 20159692






3 Functional Relationships(s)
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1 RESULTS: Compared with the control group, high-concentration FK506 (20 ng/ml) significantly inhibited the secretions of IL-2, IL-6, IL-12, IL-17, IFN-gamma, TNF-alpha, GM-CSF and G-CSF. Tacrolimus colony stimulating factor 2 Homo sapiens
2 At a moderate concentration (5 ng/ml), FK506 inhibited the secretion of GM-CSF significantly. Tacrolimus colony stimulating factor 2 Homo sapiens
3 CONCLUSION: FK506 effectively inhibits the secretion of proinflammatory cytokines including IL-6, IFN-gamma and TNF-alpha and also the secretion of IL-2, IL-12, IL-17, GM-CSF and G-CSF. Tacrolimus colony stimulating factor 2 Homo sapiens