Title : PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.

Pub. Date : 2010 Feb 17

PMID : 20159609






1 Functional Relationships(s)
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1 Genome-wide epigenetic studies revealed that treatment with pharmacological doses of all-trans retinoic acid induces changes in H3 acetylation, but not H3K27me3, H3K9me3, or DNA methylation at the PML-RARalpha/RXR binding sites or at nearby target genes. Tretinoin retinoid X receptor alpha Homo sapiens