Title : A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.

Pub. Date : 2010 Feb 12

PMID : 20159555






1 Functional Relationships(s)
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1 Here, we show that within the Hsp70, Hsp110, and Hsp40 (DNAJ) chaperone families, members of a subclass of the DNAJB family (particularly DNAJB6b and DNAJB8) are superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins. polyglutamine DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 Homo sapiens