Title : Roles of phospholipase D in phorbol myristate acetate-stimulated neutrophil respiratory burst.

Pub. Date : 2011 Mar

PMID : 20158570






2 Functional Relationships(s)
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1 Using 1-butanol, a PLD substrate, to block phosphatidic acid (PA) generation, the PMA-stimulated neutrophil respiratory burst was also partially inhibited, further indicating that PLD activation, possibly its hydrolytic product PA and diacylglycerol (DAG), is involved in PMA-stimulated respiratory burst. 1-Butanol glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 Using 1-butanol, a PLD substrate, to block phosphatidic acid (PA) generation, the PMA-stimulated neutrophil respiratory burst was also partially inhibited, further indicating that PLD activation, possibly its hydrolytic product PA and diacylglycerol (DAG), is involved in PMA-stimulated respiratory burst. 1-Butanol glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens