Title : Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study.

Pub. Date : 2010 Apr

PMID : 20156674






2 Functional Relationships(s)
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1 The data indicate that in a relatively hypoxic environment HIF-1alpha may play a role in mediating the anti-cancer effect of rapamycin and cyclophosphamide may prevent the feedback activation of Akt by rapamycin. Sirolimus hypoxia inducible factor 1 subunit alpha Homo sapiens
2 The data indicate that in a relatively hypoxic environment HIF-1alpha may play a role in mediating the anti-cancer effect of rapamycin and cyclophosphamide may prevent the feedback activation of Akt by rapamycin. Sirolimus hypoxia inducible factor 1 subunit alpha Homo sapiens