Pub. Date : 2010 May 4
PMID : 20156534
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Standard treatment of acute poisoning by organophosphorus compounds (OP) includes administration of an antimuscarinic (e.g. atropine) and of an oxime-based reactivator of OP-inhibited acetylcholinesterase (AChE). | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | A recently introduced dynamically working in vitro model with real-time determination of membrane-bound AChE activity was shown to be a very versatile and promising model to investigate oxime-induced reactivation kinetics of OP-inhibited enzyme. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | In addition, the basic kinetic constants of inhibition, aging, spontaneous- and oxime-induced-reactivation of erythrocyte AChE from these species were determined with a standard static model. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |