Pub. Date : 2010 Jan 14
PMID : 20152113
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The density of GABA(A) receptors (GABA(A)Rs) at synapses regulates brain excitability, and altered inhibition may contribute to Huntington"s disease, which is caused by a polyglutamine repeat in the protein huntingtin. | gamma-Aminobutyric Acid | huntingtin | Homo sapiens |
2 | When huntingtin is mutated, as in Huntington"s disease, GABA(A)R transport and inhibitory synaptic currents are reduced. | gamma-Aminobutyric Acid | huntingtin | Homo sapiens |