Pub. Date : 2010 Dec 5
PMID : 20149834
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Functional inactivation of triosephosphate isomerase through phosphorylation during etoposide-induced apoptosis in HeLa cells: potential role of Cdk2. | Etoposide | triosephosphate isomerase 1 | Homo sapiens |
| 2 | Among the six candidate phosphoproteins, human triosephosphate isomerase (TPI), a glycolytic enzyme, was found to be a direct substrate of Cdk2 during etoposide-induced apoptosis. | Etoposide | triosephosphate isomerase 1 | Homo sapiens |
| 3 | Among the six candidate phosphoproteins, human triosephosphate isomerase (TPI), a glycolytic enzyme, was found to be a direct substrate of Cdk2 during etoposide-induced apoptosis. | Etoposide | triosephosphate isomerase 1 | Homo sapiens |
| 4 | Loss of catalytic activity of TPI as a consequence of phosphorylation of this glycolytic enzyme may disrupt energy production in etoposide-treated HeLa cells, rendering these cells prone to undergo apoptosis. | Etoposide | triosephosphate isomerase 1 | Homo sapiens |