Title : Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies.

Pub. Date : 2010 Mar

PMID : 20145913






1 Functional Relationships(s)
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1 The assays are based on analysis and quantification by high-performance liquid chromatography-tandem mass spectrometry of glucuronides formed from selective probe substrates, namely, beta-estradiol (UGT1A1, 3-glucuronide), 1-naphthol (UGT1A6), propofol (UGT1A9), and naloxone (UGT2B7). Glucuronides UDP glucuronosyltransferase family 1 member A6 Homo sapiens