Title : Involvement of p38 MAPK- and JNK-modulated expression of Bcl-2 and Bax in Naja nigricollis CMS-9-induced apoptosis of human leukemia K562 cells.

Pub. Date : 2010 Jun 15

PMID : 20144638






1 Functional Relationships(s)
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1 Taken together, our data suggest that CMS-9-induced apoptosis of K562 cells is catalytic activity-dependent and is mediated through mitochondria-mediated death pathway triggered by Ca2+/ROS-evoked p38 MAPK and JNK activation. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens