Pub. Date : 2006 Jan
PMID : 20141508
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This is achieved either by directly coordinating to the metal ion found in some metalloenzymes (CAs, CPA, STS), usually by means of one of the nitrogen atoms present in the sulfamide motif, or, as in the case of the cyclic sulfamides, acting as HIV protease inhibitors interacting with the catalytically critical aspartic acid residues of the active site by means of an oxygen atom belonging to the HN-SO(2)-NH motif that substitutes a catalytically essential water molecule. | Nitrogen | carboxypeptidase A1 | Homo sapiens |