Title : Hirsutenone inhibits lipopolysaccharide-activated NF-kappaB-induced inflammatory mediator production by suppressing Toll-like receptor 4 and ERK activation.

Pub. Date : 2010 Apr

PMID : 20138154






1 Functional Relationships(s)
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1 Hirsutenone, dexamethasone, ERK inhibitor or Bay 11-7085 (an inhibitor of NF-kappaB activation) reduced the lipopolysaccharide-induced production of cytokines IL-1beta and IL-8, and the chemokine CCL17. hirsutenone C-X-C motif chemokine ligand 8 Homo sapiens