Title : Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic mice.

Pub. Date : 2010 Sep 15

PMID : 20136508






1 Functional Relationships(s)
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1 Acute exposure to AT(1)R blocker losartan restored the impaired endothelium-dependent dilatations in aortas of db/db mice and also in renal arteries of diabetic patients (fasting plasma glucose level > or =7.0 mmol/l). Losartan angiotensin II, type I receptor-associated protein Mus musculus