Pub. Date : 2010 Sep 15
PMID : 20136500
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Since pan-caspase inhibitor z-VAD-fmk abolished the TNF-alpha-induced mitochondrial changes, z-DEVD-fmk, an inhibitor of caspase-3 had no effect, suggesting that TNF-alpha-induced mitochondrial changes or cytochrome c and Smac release requires caspase-8 but not caspase-3 activation. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | caspase 8 | Homo sapiens |