Title : Peak half-width plots to study the effect of organic solvents on the peak performance of basic drugs in micellar liquid chromatography.

Pub. Date : 2010 Mar 12

PMID : 20132939






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The addition of the anionic surfactant sodium dodecyl sulphate (SDS) to hydro-organic mixtures of methanol, ethanol, propanol or acetonitrile with water yielded enhanced peak shape (i.e. increased efficiencies and symmetrical peaks) for a group of basic drugs (beta-blockers) chromatographed with a Kromasil C18 column. acetonitrile Bardet-Biedl syndrome 9 Homo sapiens
2 Acetonitrile seems to be superior to the alcohols in terms of peak shape, which can be interpreted by the larger reduction in the adsorbed surfactant layer on the C18 column. acetonitrile Bardet-Biedl syndrome 9 Homo sapiens